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The Future of Orthopedics:
News, Trends, and Insights from the World of Hip and Knee Replacement and Beyond

Read up on the research transforming total joint arthroplasty – and the BIOLOX® ceramic components shaping the future of patient care. 

BIOLOX®delta CoC resurfacing could ease the burden of follow-up costs

First study outlines potential cost advantage of ceramic resurfacing follow-up protocols over metal resurfacing.

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Image showing the BIOLOX® delta CoC ceramic implant within a human hip joint, with a highlighted message: “Clinically proven for 14 years” – a trusted solution for long-lasting and biocompatible hip replacement.

BIOLOX®delta delivers fracture-free implant rates after 14 years

A new multi-center study (Worthing, Lister, Cairo University) in the European Journal of Orthopaedic Surgery & Traumatology has confirmed what many surgeons know:

Ceramic-on-ceramic bearings made of BIOLOX®delta perform – and last.

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PEEK-on-ZTA ceramic returns strong five-year results in cervical total disc replacement

Dr. Richard Guyer and team from the Center for Disc Replacement at Texas Back Institute conducted a clinical trial evaluating the five-year follow-up of single-level PEEK-on-ZTA ceramic cervical TDR procedures against a control group of propensity-score-matched anterior cervical discectomy and fusion (ACDF) procedures. The material focus of this study was the Simplify Cervical Artificial Disc from Globus/NuVasive, made with zirconia-toughened-alumina (ZTA) ceramic. 

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How does cobalt-chromium-molybdenum (CoCrMo) wear contribute to cellular corrosion? An in vitro study and its implications for joint replacement

With support from AAHKS, Dr. William Mihalko, PhD, and a research team at the University of Tennessee Health Science Center set out to answer this question by conducting an in vitro examination of biological responses to simulated CoCrMo wear particles and their role in inflammatory cell-induced corrosion (ICIC).

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An infographic showing information and goals about a THR revision study in the UK.

New UK study shows THR revision least likely with BIOLOX®delta ceramic bearings

Sourcing from one of the world’s largest registries – the UK’s National Joint Registry – Dr. Whitehouse and team at the University of Bristol Medical School have analyzed the efficacy of multiple bearing surface materials in primary total hip replacement (THR). They analyzed 1,026,481 THRs performed from 2003-2019, 2% of which (20,869) required revision.

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An infographic summarizing the clinical takeaway from a case study on ceramic-on-ceramic bearings in hip revision.

Bearing Selection in Hip Revision: Why It Matters for Long-Term Success

Prof. Simon Marmor and team from the Department of Orthopedic Surgery, Groupe Hospitalier Diaconesses Croix Saint-Simon in Paris faced an unusual case of a painful hip with tissue pigmentation on a 68-year-old male patient, which had been revised with a metal bearing three years earlier in another institution.

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Metal release in the knee: A greater burden than suspected?

An interdisciplinary US team – including Clemson University’s Jeremy Gilbert, PhD, Drexel University’s Steve Kurtz, PhD, and the University of Tennessee’s William Mihalko, MD, respectively in Clemson, Philadelphia, and Memphis – have studied the mechanisms that cause the deterioration of cobalt-chrome-molybdenum (CoCrMo) and titanium components in total knee arthroplasty (TKA) and releasing metal ions in vivo. They conclude that ALTRs, electrocautery damages, and other damages may interfere as dangerously in primary TKA implants as in hip implants.

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Surgeons can expand their options with 40mm BIOLOX®delta CoC heads and bearings

Finding optimal head and bearing sizes is an ongoing journey in total hip arthroplasty (THA). Large-diameter ceramic-on-ceramic (CoC) bearings may improve function and implant stability while minimizing wear concerns, and there is a growing body of evidence to support the implementation of larger sizes.

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Safe Ingrowth: Comparable Migration Patterns of Ceramic and Polyethylene Liners in THA at 5 years

Aseptic loosening continues to challenge the outcomes of total hip arthroplasty (THA). While highly cross-linked PE (HXLPE) liners have effectively reduced wear rates, ceramic-on-ceramic (CoC) bearings exhibit even lower rates, promising enhanced durability.
However, the stiffness of ceramic compared to XLPE is often perceived to compromise osseointegration by altering stress distribution at the bone-implant interface.

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