Expertise in Bioceramics

Today’s healthcare environment is constantly evolving. Due to cost pressure and a challenging regulatory framework there is an increasing demand for high quality products with more focus on patient and clinical outcomes. The choice of the implant material and its long-term consequences for the patient and the healthcare system play a pivotal role in total joint arthroplasty.

BIOLOX® ceramics are considered a benchmark in ceramic joint replacement. All of the world’s leading orthopedic manufacturers offer hip joint replacement systems featuring BIOLOX® ceramic components. No other manufacturer’s material is used as often for hip bearing couples as the pink BIOLOX®delta ceramics. Our close collaborative partnership with orthopedic manufacturers, material scientists and surgeons is a fundamental cornerstone of this success. 

BIOLOX® Success Story

At CeramTec we can proudly look back on more than 45 years of experience in the development and manufacturing of innovative ceramic solutions for medical applications. 

Our material has developed from BIOLOX®, established in 1974, to BIOLOX®delta introduced in 2003. The excellent biological behaviour of ceramics in medicine has been well documented. 

  • More than 20 million BIOLOX® components sold since 1974
  • More than 15 years of clinical experience with BIOLOX®delta ceramics
  • Best clinical outcomes with ceramic bearings1,2
  • Low revision rates with ceramic bearings1,2

The Partner You Have Been Looking For

We partner with you and support you every step along the way with our adjacent services. From the start of your innovation process till product launch and beyond. Our broad range of services reflects the complete product life cycle workflow from ideation over engineering, manufacturing, regulatory through marketing and education. Challenge us to achieve your desired level of differentiation!

Learn more about our Services

Implant Material

Ceramic implants are 100% metal-free. Therefore, patients with metal sensitivity find a viable choice with ceramic implants and bearing materials. Ceramics such as BIOLOX®delta show excellent biocompatibility3,4,5 and are chemically stable in the physiological environment.6,7,8 More than 45 years of clinical experience and scientific research have shown that adverse reactions to ceramic particles are very unlikely.5,9,10

More about our ceramic materials

Image: high resolution SEM (scanning electron microscope) image showing a detail of bioceramic-osteoblast interface.
Clinical experience shows no long-term adverse reactions to ceramic particles.

Clinical Outcomes

The use of ceramic bearings in hip arthroplasty has been rising steadily over the last years. Ceramic is meanwhile the preferred femoral head material in hip replacement. There is a consensus that the biological advantages of ceramics contribute to improve the clinical outcomes and possibly do not compromise the patient’s health even in association with comorbidities.

How does the material impact the clinical outcome?

Cost-Effectiveness in THA

A cheaper implant doesn't necessarily save money. As a result of the steady increase in younger patients who still work, postoperative complications can have costly consequences. A cost-effective solution in THA encompasses all costs related to the intervention and contributes to the best clinical outcome. An important factor is the choice of an implant material with very low biological reactivity and minimal adverse reactions even in active and young patients. 

What is a cost-effective solution in THA?

Achieving cost effectiveness in THA with ceramic implants.

BIOLOX® Products on Display


BIOLOX CONTOURA® is a femoral head mimicking the anatomical shape of the femur head. BIOLOX CONTOURA® heads retain the outer diameter profile of conventional implants and incorporate a contoured shoulder with a lesser radius to reduce the volume of material exposed to the soft tissue. The contoured design provides a smooth transition throughout the femoral head and the head-neck junction. 

  • Reduced volume and radius underneath equator
  • Reduced potential for interaction with surrounding tissues
  • Same size as a conventional design
  • Same stability provided as with a conventional head design

Download the BIOLOX CONTOURA® Product Information

Sleeved Revision Femoral Head

BIOLOX®OPTION offers the possibility of revising a femoral head implant while retaining a well-fixed femoral stem with minor damage on the taper surface. The adapter sleeve is designed to recreate a pristine taper interface for the ceramic head before it is placed on a stem which remains in situ. BIOLOX®OPTION also offers the possibility of adjusting the offset intraoperatively in primary hip replacement.

More info on our sleeved femoral head as PDF

BIOLOX® Ceramic Hip Components

The benchmark in joint replacement: BIOLOX®delta femoral heads and cup inserts for hip replacement can be combined with ceramic components from the BIOLOX® family as well as with inserts made from conventional and highly cross-linked polyethylene.

BIOLOX® Hip Product Portfolio

Ceramic-on-Ceramic Resurfacing

On display the H1 ceramic-on-ceramic resurfacing of Embody

  • Anatomically derived contour
  • Cementless fixation
  • Vacuum-Plasma-Coating
Metal Free Ceramic Knee

On display, the BPK-S ceramic knee of Peter Brehm.

  • First full ceramic knee system11
  • No known risk of allergy11
  • Lower wear of PE against ceramic (compared to metal)11
BIOLOX®delta ceramics at a glance

Download the benefits of BIOLOX®delta in orthopaedics. 

Product Information
BIOLOX®delta at a glance
1,018 KB, pdf

Discover the Future

BIOLOX® Spinal Implant
click for full image
BIOLOX® Shoulder Implant
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BIOLOX® Ankle Implant
click for full image

For further information please contact our Head of Commercial Development, Werner Fischer, phone
+ 49 7153 611 845 or via email

For further information please contact our Head of Commercial Development, Werner Fischer, phone
+ 49 7153 611 845 or via email

For further information please contact our Head of Commercial Development, Werner Fischer, phone
+ 49 7153 611 845 or via email

BIOLOX® ceramics are safe in terms of metal ion release.
BIOLOX® ceramics are hypoallergenic.
BIOLOX® ceramic bearings are associated with lower risk of PJI.
BIOLOX® ceramic bearings are associated with lower risk of PJI.
BIOLOX® Keramik hat großes Potential für die Kostenwirksamkeit in der Hüft-Totalendoprothetik
BIOLOX® ceramics show a high potential for cost-effectiveness in THA.
BIOLOX® ceramics are hypoallergenic.
BIOLOX® ceramics are safe in terms of metal ion release.

Issue # 12021


CeraNews to the Point delivers an overview of relevant current research around the following key topics: Implant Material, Outcome Research and Health Economics & Policy. We trust that you will find the selected summaries both relevant and valuable.

Guest Editor

Prof. Justin P Cobb
Imperial College
London UK

Health Economics & Policy

Burden of Disease: Can the Curve Be Flattened?

The growing number of hip arthroplasty procedures requires solutions and adequate planning to reduce the future burden of disease and its economic consequences. As revision has a severe impact on the patient’s quality of...

Outcomes Research

Excellent Outcomes with BIOLOX®delta in Revision: Don't Forget the Sleeve

Introduced to the market over 15 years ago, BIOLOX®delta ceramic hip implants have been widely used in primary THA ever since. Recent studies support their value as a reliable solution in hip revision, too. Placing a...

Implant Material

Sleeved Ceramic Heads: Versatile, Essential and Proven

In hip revision, the metal taper of an otherwise intact and well-fixed stem can exhibit varying types of damage which may be attributed to assembly or disassembly damage as well as black debris indicating fretting or even...

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1. Sharplin P, Wyatt MC, Rothwell A, Frampton C, Hooper G. Which is the best bearing surface for primary total hip replacement? A New Zealand Joint Registry study. Hip Int. 2018;28(4):352-362. doi:10.5301/hipint.5000585.

2. Peters RM, Van Steenbergen LN, Stevens M, Rijk PC, Bulstra SK, Zijlstra WP. The effect of bearing type on the outcome of total hip arthroplasty. Acta Orthop. 2018;89(2):163-169. doi:10.1080/17453674.2017.1405669.

3. Maccauro G, Cittadini A, Magnani G, Sangiorgi S, Muratori F, Manicone PF, Rossi Iommetti P, Marotta D, Chierichini A, Raffaelli L, Sgambato A. In vivo characterization of Zirconia Toughened Alumina material: a comparative animal study. Int J Immunopathol Pharmacol. 2010;23(3):841-846. doi:10.1177/039463201002300319.

4. Cunningham BW, Hallab NJ, Hu N, McAfee PC. Epidural application of spinal instrumentation particulate wear debris: a comprehensive evaluation of neurotoxicity using an in vivo animal mode. J Neurosurg Spine. 2013;19:336-350. doi:10.3171/2013.5.SPINE13166.

5. Asif I M. Characterisation and Biological Impact of Wear Particles from Composite Ceramic Hip Replacements. [PhD thesis]. Leeds, UK: University of Leeds; 2018. Accessed March 6, 2020.

6. Beraudi A, Stea S, De Pasquale D, et al. Metal ion release: also a concern for ceramic-on-ceramic couplings? Hip Int. 2014;24(4):321-326. doi:10.5301/hipint.5000132.

7. Kretzer JP, Mueller U, Streit MR, et al. Ion release in ceramic bearings for total hip replacement: Results from an in vitro and an in vivo study. Int Orthop. 2018;42(1):65-70. doi:10.1007/s00264-017-3568-1.

8. Thomas P, Stea S. Metal Implant Allergy and Immuno-Allergological Compatibility Aspects of Ceramic Materials. Heidelberg, Germany:  Springer-Verlag Berlin Heidelberg; 2015.

9. Tsaousi A, Jones E, Case CP. The in vitro genotoxicity of orthopaedic ceramic (Al2O3) and metal (CoCr alloy) particles. Mutat Res. 2010;697(1-2):1-9. doi:10.1016/j.mrgentox.2010.01.012.

10. Esposito C, Maclean F, Campbell P, Walter WL, Walter WK, Bonar SF. Periprosthetic tissues from third generation alumina-on-alumina total hip arthroplasties. J Arthroplasty. 2013;28(5):860-866. doi:10.1016/j.arth.2012.10.021.

11. Trieb K, Ullmann D, Metzinger K, et al. Prospective Comparison of a Metal-Free Ceramic Total Knee Arthroplasty with an Identical Metal System. Z Orthop Unfall. 2018;156(1):46-52. doi:10.1055/s-0043-118600.

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