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News, Trends, and Insights from the World of Hip and Knee Replacement and Beyond

Read up on the research transforming total joint arthroplasty – and the BIOLOX® ceramic components shaping the future of patient care. 

3D render of a BIOLOX® ceramic femoral head and acetabular insert as a ceramic-on-ceramic bearing pair, labeled Clinical Results

Ceramic-on-ceramic tribology is a system & technology question – not a material question alone.

CoC bearings have proven their long-term stability and performance in total hip arthroplasty. But what do we know about the mechanisms behind frictional instability, lubrication transitions, and microstructural damage? A research team at China’s Zhejiang Institute of Medical Device Testing set out to consolidate the current evidence.

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3D render of a BIOLOX®delta ceramic-on-ceramic hip resurfacing implant with clinical results headline.

BIOLOX®delta Ceramic-on-Ceramic Hip Resurfacing: Wear Performance Under Daily Activities

A new wear simulation study jointly published by Prof. Louise Jennings and Raelene Cowie (University of Leeds) and MatOrtho Ltd’s engineering team Danielle de Villiers, Colin Fisher, et al. evaluates the tribological performance of MatOrtho’s ReCerf® ceramic-on-ceramic hip resurfacing (BIOLOX®𝘥𝘦𝘭𝘵𝘢) over a range of daily activities (e.g. walking, jogging). The study moves beyond the standard ISO 14242-1 gait cycle to bearing behavior under more patient-realistic conditions.

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Three THA bearing interfaces side by side: ceramic-on-ceramic, ceramic-on-polyethylene, and metal-on-polyethylene components

How do bearing-surface choices in total hip arthroplasty perform across patient age and follow-up duration?

Bearing selection in THA is not a one-size-fits-all decision. A new network meta-analysis of 59 randomized controlled trials (RCTs) now quantifies what that means, stratified by patient age and follow-up duration.

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Microscopic view of porous ceramic scaffold with study parameters: Y-TZP, ZTA, 60–70% porosity, ovine model, 12–24 weeks.

How might porous ceramic scaffolds aid in bone regeneration? New research dives in.

Bone regeneration after large and complex defects (of which there are about 7 million per year in the US) remains a clinical challenge, particularly when it comes to identifying a scaffold material that combines strong mechanical performance and biological effectiveness.

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Title picture of retrieval analysis on metal fatigue in revision total knee arthroplasty.

About metal fatigue: an underestimated failure mechanism of metal modular knee implants

A retrieval analysis published in the Journal of Orthopaedic Research by Dr. Steve Kurtz et al. (Drexel University) highlights the underestimated risks of metal-related complications in revision total knee arthroplasty (TKA). Although revision TKA remains a laborious and technically demanding procedure, it is generally associated with good clinical outcomes, albeit inferior to those of primary TKA. This study highlights a critical yet under-studied failure mechanism on a microscopic scale: metal fatigue.

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Infographic: headline "Unraveling Wear – What Really Drives THA Longevity?" with hip joint schematic and clinical results label

Which factors really drive long-term performance in total hip arthroplasty?

A new systematic review from Nikam et al. (Manipal Academy of Higher Education, India, & Izmir Institute of Technology, Turkey) synthesizes the results of 109 studies conducted between 2010-2025 to revisit a recurrent question in orthopedics: implant longevity.

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BIOLOX® ceramic femoral head and acetabular insert with clinical results banner and ceramic fracture graphic

Outcomes of revision for ceramic fracture in Dual Mobility implants with a metallic inner head

Ceramic component fracture is rare in total hip arthroplasty (THA), but when it occurs, the choice of revision bearing can significantly influence long-term patient outcomes.

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Skeleton with joint implant icons; metal particles dispersing toward a brain — illustrating systemic metal migration in total joint arthroplasty.

What implications does implant material choice carry beyond the joint itself?

We know from recent evidence that metal implant debris and metal ions don’t stay only at the joint. They travel to the heart, liver, spleen, kidneys, and bone marrow. But do they reach the brain? And if they do, what happens there?

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Ceramic femoral head in a white acetabular cup, labeled Clinical Results — illustrating Prozyr® zirconia-on-polyethylene bearing in THA.

A 25-year lesson from ceramic hip bearings

A new study by Ishida, Takahashi, Tateiwa, et al. followed 62 hips for over 20 years, comparing 31 monolithic zirconia ceramic-on-polyethylene (Prozyr®, Saint Gobain Desmarquest) with 31 cobalt-chromium metal-on-polyethylene bearings.

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